Safety of Apixaban for Postoperative Venous Thromboembolism Prophylaxis After Bariatric Surgery: A Single-Centre Retrospective Cohort Study - PubMed
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- #Apixaban
- #VTE Prophylaxis
- #Bariatric Surgery
- Study evaluates safety of apixaban for VTE prophylaxis post-bariatric surgery in 540 patients at a tertiary center.
- Adverse events occurred in 5.2% of patients, primarily clinically relevant non-major bleeding (3.0%) and skin rash (2.2%).
- No symptomatic VTE or major bleeding events observed within 90 days, supporting apixaban's favorable short-term safety profile.
- All adverse events occurred in women, highlighting a sex-specific risk that may require targeted counseling.
- Apixaban administered as 2.5 mg twice daily starting around 72 hours post-surgery and continued for 30 days.