Multi-modal AI for comprehensive breast cancer prognostication - PubMed
3 hours ago
- #AI pathology test
- #risk stratification
- #breast cancer prognosis
- A multi-modal AI test integrating digital pathology and clinical data was developed using data from 8161 patients.
- The AI test showed robust prognostic performance, predicting disease-free interval with a C-index of 0.71 and HR of 3.63.
- It outperformed the standard-of-care 21-gene assay in discrimination, with a C-index of 0.67 vs. 0.61.
- The test demonstrated strong prognostic ability across all molecular subtypes, including triple negative breast cancer.
- This AI-based pathology test has the potential to improve risk stratification and clinical decision-making in breast cancer.