Composite outcome measures that successfully differentiate active treatments from placebo in psoriatic arthritis trials: a GRAPPA-OMERACT systematic review and network meta-analysis - PubMed
5 hours ago
- #network meta-analysis
- #psoriatic arthritis
- #composite outcome measures
- Systematic review identified composite outcome measures most effective at distinguishing active treatments from placebo in psoriatic arthritis trials.
- Network meta-analysis showed MDA and PASDAS had superior discriminant capacity compared to DAPSA, with ACR20 also outperforming DAPSA.
- Sensitivity analyses supported consistent advantages for MDA and PASDAS, and exploratory analyses indicated ACR70 had greater discriminant capacity than ACR20 and DAPSA.