Skin aging: mechanisms, evaluation, and rejuvenation - PubMed
3 hours ago
- #rejuvenation
- #regenerative_medicine
- #skin_aging
- Skin aging is a visible indicator of overall aging, affecting barrier integrity, immune function, and regeneration.
- Mechanisms include intrinsic cellular senescence, disrupted communication between skin layers, microbiome dysregulation, and hormonal changes.
- Advances in quantitative evaluation allow objective measurement of skin aging through molecular, morphological, and microbial indices.
- Rejuvenation strategies involve gene expression rewiring, metabolic modulation, microenvironment remodeling, microbiome adjustment, and hormone regulation.
- The study provides a framework for precision interventions and next-generation regenerative therapies targeting skin aging.