Prevalence and prognostic role of untreated moderate-to-severe tricuspid regurgitation: a systematic review and meta-analysis - PubMed
5 hours ago
- #mortality risk
- #tricuspid regurgitation
- #prognostic meta-analysis
- Untreated moderate-to-severe tricuspid regurgitation (TR) has a prevalence of 13.5% across studied populations, but varies widely among subgroups.
- Moderate-to-severe TR significantly increases all-cause mortality compared to none-to-mild TR, with an unadjusted hazard ratio (HR) of 2.07.
- The increased mortality risk holds after adjustment and across most patient subgroups, including those with left-side valvular heart disease and heart failure.
- Mortality risk shows a stepwise increase with greater TR severity.
- Moderate-to-severe TR is also linked to higher risks of cardiovascular mortality and heart failure hospitalization.