Antimicrobial susceptibility and resistance gene profiles of Prevotella spp. isolated in Oita University Hospital, Japan - PubMed
3 hours ago
- #Anaerobic Bacteria
- #Prevotella Species
- #Antimicrobial Resistance
- Study evaluated antimicrobial susceptibility and resistance gene profiles of 51 Prevotella spp. isolates from Oita University Hospital, Japan (2011-2025).
- Resistance rates: ampicillin 47%, clindamycin 39%, metronidazole 4%; no resistance to sulbactam-ampicillin, tazobactam-piperacillin, or meropenem.
- MINO MIC50/MIC90 values were 0.25 mg/L and 4 mg/L; tetQ gene associated with high MINO MICs.
- Resistance gene prevalence: cfxA 61%, ermF 55%, tetQ 27%, nim 2%; MNZ-resistant isolates lacked nim gene.
- Highlights need for continued surveillance of Prevotella spp. resistance patterns in Japan to guide antimicrobial therapy.