Spatial distribution of the proteome in the human body and in cancers - PubMed
3 hours ago
- #proteome
- #spatial distribution
- #cancer
- A comprehensive human proteomic landscape was generated using data-independent acquisition mass spectrometry, profiling over 13,000 proteins across 2,856 samples.
- The dataset covers 58 major tissue types, 251 specific tissue subtypes, and 25 distinct carcinomas, enabling spatially resolved proteome analysis across various physiological states.
- This resource provides insights into developmental processes and oncogenic progression, and aids in identifying organ-specific toxicity, repurposable anticancer drugs, and therapeutic targets for cancers.