Cytotoxicity assessment of LuxCreo and Nylon direct-printed photopolymers for orthodontic applications: An in vitro study - PubMed
3 days ago
- #orthodontic materials
- #cytotoxicity
- #biocompatibility
- Evaluated cytotoxicity of two direct-printed photopolymers, LuxCreo and Nylon, for orthodontic use.
- Compared to conventional materials (PETG, PMMA), both direct-printed materials reduced cell viability at certain time points.
- Nylon reduced metabolic activity at all intervals (24h, 72h, 7 days), while LuxCreo only at 72h and 7 days.
- No significant cell death was induced by any materials in human gingival fibroblasts.
- Elevated pro-inflammatory cytokines (IL-6, IL-8) were observed only with Nylon; IL-1β levels remained unchanged.
- Study highlights need for further research into cytotoxicity mechanisms and clinical safety of direct-printed orthodontic materials.