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Association of obstructive airway disease with COMISA: findings from the Turkish sleep apnea database (TURKAPNE) cohort - PubMed

3 hours ago
  • #COMISA
  • #Sleep Disorders
  • #Obstructive Airway Disease
  • The study investigates the link between obstructive airway diseases (OAD), such as asthma and COPD, and COMISA (comorbid insomnia and sleep apnea) using data from 12,715 adults in the Turkish Sleep Apnea Database (TURKAPNE).
  • Results show that OAD was present in 12.2% of participants, and COMISA prevalence was significantly higher in those with OAD (16.1%) compared to those without (10.8%).
  • After adjusting for factors like age, sex, BMI, education, smoking, and comorbidities, OAD remained independently associated with COMISA, with an adjusted odds ratio of 1.19.
  • Patients with both COMISA and OAD exhibited more adverse features, including older age, higher obesity rates, shorter total sleep time, and poorer nocturnal oxygenation.
  • The study highlights the need for integrated and personalized management strategies for patients with OAD and COMISA due to their compounded negative impacts on health outcomes and quality of life.