Current concepts on feeding the critically ill patient: a narrative review - PubMed
4 hours ago
- #Personalized Therapy
- #ICU Management
- #Critical Care Nutrition
- Nutritional therapy is essential in critical care but requires personalized, phase-specific approaches due to patient heterogeneity and metabolic changes.
- Inflammation influences nutritional responsiveness, with highly inflamed patients facing reduced benefits and higher overfeeding risks.
- Personalized strategies include indirect calorimetry, fat-free mass-based protein dosing, and metabolic biomarkers for tailored therapy.
- Micronutrient deficiencies are common in critically ill patients and need structured assessment and supplementation.
- Macronutrient delivery should be escalated progressively and aligned with disease phase and organ function.
- Ketogenic diets show feasibility and potential benefits in neurocritical care and sepsis.
- Post-ICU phases involve persistent catabolism and underfeeding, necessitating structured rehabilitation and transitional nutrition programs.
- Future strategies may rely on metabolic phenotyping and biomarker-informed stratification rather than uniform targets.
- Further robust clinical trials are needed to confirm the impact of personalized nutrition on long-term outcomes.