Salivary Free Testosterone as a Potential Biomarker for Pelvic Organ Prolapse in Postmenopausal Women: A Prospective Case-Control Study - PubMed
3 days ago
- #hormone biomarkers
- #postmenopausal health
- #pelvic floor disorders
- Salivary free testosterone levels are significantly lower in postmenopausal women with pelvic organ prolapse (POP) compared to controls.
- Advanced stages of POP (III-IV) are associated with further reductions in salivary free testosterone levels.
- Serum DHEA-S levels are higher in women with POP, contrary to expectations, and elevated in stages II and III compared to controls.
- No significant difference was found in estradiol levels between the POP and control groups.
- The POP group had higher BMI, greater parity, and more severe lower urinary tract symptoms than the control group.
- Salivary free testosterone is suggested as a non-invasive biomarker for assessing POP risk and severity in postmenopausal women.