Albuminuria and heart failure - PubMed
2 hours ago
- #Risk Stratification
- #Heart Failure
- #Albuminuria
- Albuminuria (measured by urinary albumin-to-creatinine ratio) is present in nearly half of heart failure patients.
- It is an independent risk marker for incident heart failure and poor outcomes in existing heart failure, even at low levels.
- Current heart failure guidelines do not universally recommend routine albuminuria screening, unlike guidelines for diabetes, chronic kidney disease, and hypertension.
- Emerging data suggest this lack of screening may limit early detection, risk stratification, and treatment opportunities.
- Clinical trials show that reducing albuminuria with therapies like renin-angiotensin inhibitors, SGLT2 inhibitors, and finerenone lowers risks for cardiovascular and kidney outcomes.
- Albuminuria may function as both a risk marker and a modifiable factor in heart failure management.