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Treatment of Clinically Diagnosed Alzheimer's Disease by External Counterpulsation A Randomized Clinical Trial - PubMed

3 days ago
  • #Alzheimer's disease
  • #cognitive function
  • #external counterpulsation
  • External counterpulsation (ECP) was tested in a 12-month randomized, sham-controlled trial for early Alzheimer's disease.
  • ECP significantly improved activities of daily living (ADCS-ADL) and cognitive function (VADAS-cog) compared to sham at 12-24 weeks.
  • Benefits persisted for up to 52 weeks, even though treatment stopped at 6 months.
  • The therapy involved 35 one-hour sessions, initially frequent then reduced, with no serious device-related adverse events.
  • The study suggests ECP as a promising novel therapeutic approach for early AD, warranting further investigation.