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A mosaic of whole-body representations on the human precentral gyrus - PubMed

3 hours ago
  • #motor cortex
  • #neuroscience
  • #brain mapping
  • A comprehensive single-neuron resolution map of the human motor cortex was created using microelectrode array recordings from 8 individuals with paralysis.
  • The precentral gyrus (PCG) exhibits highly intermixed whole-body representations, with all body parts represented across sampled locations, though strength aligns roughly with the motor homunculus.
  • Two speech-preferential areas were identified, separated by a broadly tuned orofacial-dominant region.
  • Limb movement representations were interlinked throughout the PCG, with homologous movements (e.g., toe curl and hand close) showing correlated activity.
  • The findings support an intermixed, interrelated, and behavior-centered organization of the motor cortex, providing targeting insights for brain-computer interfaces.