Association between initial benzodiazepine prescribing patterns and time to benzodiazepine discontinuation: A population-based retrospective cohort study - PubMed
4 hours ago
- #medication discontinuation
- #benzodiazepine prescribing
- #population study
- Longer initial benzodiazepine prescriptions (over 7 days) are associated with a lower likelihood of discontinuation.
- Being prescribed two or more benzodiazepines versus one reduces the likelihood of discontinuation.
- Prescribing long-acting benzodiazepines or a combination of short and long-acting ones reduces discontinuation likelihood compared to short-acting alone.
- Higher daily doses (>20 DME) are linked to reduced discontinuation likelihood, while moderate doses (5-20 DME) slightly increase it.
- Shorter initial courses, using a single benzodiazepine, and preferring short-acting agents may reduce long-term benzodiazepine use.