Cannabinoids: Therapeutic Applications, Mechanisms, and Challenges in Modern Medicine - PubMed

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Cannabinoids are active compounds from Cannabis sativa, with over 480 types discovered, including 110 phytocannabinoids.
Important components include Δ-9-THC, CBD, CBG, CBN, CBC, and CBGVA; CBD is noted for non-psychotic effects and therapeutic benefits.
Cannabinoids have therapeutic applications such as pain management, treating cancer, stress, neurological disorders, and improving immunity and skin health.
Commercially available derivatives like nabilone are used to relieve chemotherapy-induced emesis in cancer patients.
Common side effects include nausea, dizziness, fatigue, sedation, and anxiety.
In vitro and preclinical studies support cannabinoid efficacy, but clinical trials are needed to establish standard formulations, doses, and safety profiles.

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