Plasma Biomarkers for Alzheimer's Disease Across the Continuum: A Systematic Review of SIMOA-Based Studies - PubMed
3 hours ago
- #SIMOA Technology
- #Blood Biomarkers
- #Alzheimer's Disease
- The review focuses on plasma biomarkers for Alzheimer's disease (AD) using ultrasensitive SIMOA technology.
- Key biomarkers discussed include β-amyloid (Aβ42, Aβ40, ratio), tau (t-Tau, p-Tau181, p-Tau231, p-Tau217), neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP).
- Blood-based biomarkers offer a less invasive and costly alternative to traditional methods like lumbar puncture and neuroimaging.
- Findings indicate promise for early AD diagnosis, but further validation is needed before clinical use.