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Smoking Cessation, Weight Change, and Risk of Dementia: A Prospective Cohort Study - PubMed

3 hours ago
  • #dementia risk
  • #smoking cessation
  • #weight gain
  • Smoking cessation is associated with a lower dementia risk and slower cognitive decline, comparable to never smokers.
  • Benefits are largely limited to individuals with no or modest postcessation weight gain (≤5 kg over 2 years).
  • Weight gain >10 kg after quitting may attenuate these benefits and not show significant dementia risk reduction.
  • The dementia risk reduction approaches that of never smokers and plateaus around 7 years after cessation.
  • Smoking cessation is linked to long-term slower cognitive decline but no transient cognitive changes.
  • Study suggests weight management should be integrated into smoking cessation programs to optimize benefits.