Associations of allergic diseases with incident hospital-recorded osteoporosis and major osteoporotic fracture in older adults: a prospective cohort study in the UK Biobank - PubMed
4 hours ago
- #Older Adults
- #Allergic Diseases
- #Osteoporosis Risk
- Asthma was associated with a 20% increased risk of major osteoporotic fracture and a 45% increased risk of hospital-recorded osteoporosis.
- Coexistence of allergic rhinitis and asthma was linked to a 36% higher risk of major osteoporotic fracture and a 46% higher risk of hospital-recorded osteoporosis.
- Allergic disease burden showed a graded association with both osteoporosis and fracture outcomes.
- The study involved over 190,000 UK Biobank participants aged 60+, with a median follow-up of 13.8 years.
- Associations were adjusted for sociodemographic, lifestyle, psychosocial, and comorbidity factors and were robust across sensitivity analyses.
- Findings suggest that asthma and greater allergic disease burden may be risk factors for bone health issues in older adults.