Comparative efficiency of leucine-rich alpha-2 glycoprotein and fecal calprotectin to assess endoscopic activity in Crohn's disease: a prospective observational study - PubMed
3 hours ago
- #biomarker
- #Crohn's disease
- #endoscopic remission
- Study compared leucine-rich alpha-2 glycoprotein (LRG) and fecal calprotectin (FC) for assessing endoscopic activity in Crohn's disease.
- LRG demonstrated significantly higher sensitivity (85.9%) than FC (70.3%) for endoscopic remission using cutoff values of 11 µg/mL and 100 µg/g, respectively.
- In multivariate analysis, only LRG was an independent factor associated with endoscopic remission (odds ratio 3.016).
- Conclusion: LRG may be a more useful non-invasive biomarker for endoscopic activity in Crohn's disease compared to FC.