Cardiac Arrhythmias Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis - PubMed
3 hours ago
- #Meta-Analysis
- #Immune Checkpoint Inhibitors
- #Cardiac Arrhythmias
- Systematic review and meta-analysis assesses incidence of cardiac arrhythmias associated with immune checkpoint inhibitors (ICIs).
- Pooled incidence of arrhythmias from 13 studies involving 31,542 patients is 6.89% (95% CI: 4.4-9.4%).
- Subgroup analysis shows atrial fibrillation incidence at 6.8% (95% CI: 0.0-15.3%) and conduction disorders at 1.44% (95% CI: 0.0-3.07%).
- High heterogeneity (I² up to 99.07%) limits precision, indicating need for prospective studies with standardized monitoring.