Spironolactone and clinical outcomes in patients with alcohol use disorder and comorbid hypertension: a target trial emulation study - PubMed
3 days ago
- #spironolactone
- #alcohol use disorder
- #target trial emulation
- Spironolactone prescription is associated with a higher hazard rate for alcohol use disorder (AUD) remission compared to other antihypertensive medications.
- The study found a lower hazard rate for alcohol intoxication in patients prescribed spironolactone versus most other antihypertensives.
- This real-world evidence supports spironolactone's potential as a pharmacotherapy for AUD, warranting randomized controlled trials for further validation.