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Physical function frailty trajectory before and after cardiovascular event among older adults in three multinational cohorts - PubMed

3 hours ago
  • #Cardiovascular Disease
  • #Frailty Trajectory
  • #Older Adults
  • Physical function frailty was assessed by mobility and daily function scores among 23,307 participants over 50 from ELSA, HRS, and CHARLS cohorts.
  • Participants who developed CVD showed higher baseline physical function frailty compared to CVD-free individuals, with frailty present before the event and worsening after.
  • Short-term increases in mobility scores were observed after CVD diagnosis across all cohorts, and the annual rate of frailty increase accelerated post-event.
  • Patterns were consistent for heart disease, its subtypes (angina, heart attack, coronary heart disease, heart failure), and stroke.
  • Recommendations include integrating frailty screening into primary care for older adults and developing tailored cardiac rehabilitation programs for CVD survivors.