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ERS/ESGE/ESTS clinical practice guidelines on endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer - PubMed

3 hours ago
  • #clinical guidelines
  • #endosonography
  • #lung cancer
  • Guidelines recommend endosonography (EBUS-TBNA and EUS-FNA) over mediastinoscopy for mediastinal nodal tissue staging in suspected or confirmed NSCLC.
  • Systematic staging is suggested as the minimal standard, with combined EBUS-TBNA and EUS(-B)-FNA preferred over EBUS-TBNA alone.
  • Add-on mediastinoscopy after negative endosonography is not recommended, and endosonography is suggested for re-staging after induction therapy.
  • EBUS-TBNA and EUS(-B)-FNA are recommended for centrally located tumors adjacent to major airways or esophagus, and both are suggested for left adrenal gland analysis.
  • Competence acquisition should occur in a simulation-based environment with valid assessment methods, and 21G/22G TBNA needles are standard, with insufficient evidence for alternative needles or cryobiopsy.
  • EBUS-TBNA is highly suitable for PD-L1 assessment, providing accurate, minimally invasive diagnosis and staging of lung cancer.