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Identification of the CYP19A1-GPER1 axis as a critical oncogenic driver in hepatocellular carcinoma via AKT activation - PubMed

3 hours ago
  • #CYP19A1-GPER1 Axis
  • #Hepatocellular Carcinoma
  • #AKT Activation
  • CYP19A1 overexpression correlates with advanced HCC stages and poor survival.
  • The CYP19A1-GPER1 axis drives HCC progression via AKT activation, affecting proliferation and metastasis.
  • Targeting the CYP19A1-GPER1 axis could be a promising therapeutic strategy for hepatocellular carcinoma.