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Maternal Intellectual and Developmental Disabilities and Infant Outcomes - PubMed

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  • #Developmental Disabilities
  • #Maternal Health
  • #Infant Outcomes
  • Maternal intellectual and developmental disabilities (IDDs) are associated with significantly higher risks of adverse infant outcomes, including neonatal intensive care unit (NICU) admission, small-for-gestational-age (SGA) birth, preterm birth (PTB), and very PTB.
  • Among IDD subtypes, risks were highest for chromosomal differences, other IDDs (e.g., fetal alcohol syndrome), and intellectual disability.
  • Key maternal health conditions like preexisting hypertension, epilepsy, and mental health issues substantially contributed to these risks, particularly for NICU admission, highlighting potential targets for preconception and prenatal interventions.
  • The study used data from 6,435,742 singleton births in California (2007-2021), with 4,492 births to mothers with IDD diagnoses, analyzed through linked vital statistics and hospital records.