Association of serum uric acid with cardiovascular-kidney-metabolic syndrome in elderly populations: results from Chinese and US cohorts - PubMed
3 hours ago
- #CKM syndrome
- #elderly health
- #serum uric acid
- Study investigates the link between serum uric acid (SUA) and cardiovascular-kidney-metabolic (CKM) syndrome in elderly populations using data from Chinese and US cohorts.
- High prevalence of CKM syndrome (stages 1-4) observed: 98.33% in the SFCEC cohort and 98.76% in the NHANES cohort.
- Each 1 mg/dl increase in SUA associated with elevated CKM risks (24.9% in SFCEC, 27.8% in NHANES) after adjustment.
- Highest tertile of SUA linked to significantly increased CKM risks compared to lowest tertile in both cohorts, with odds ratios around 1.97.
- Restricted cubic spline analysis shows a positive linear dose-response relationship between SUA levels and CKM staging.
- Significant interaction by sex suggests potential sex differences in the SUA-CKM association, requiring further investigation.