High-throughput generation of patient-derived cancer stem cells for precision medicine using a microwell-chip platform - PubMed
2 hours ago
- #Cancer Stem Cells
- #Microwell Chip
- #Precision Medicine
- A microwell chip platform enables high-throughput generation of uniform micro-tumourspheres (MTSs) from limited breast cancer patient samples.
- MTSs recapitulate cancer stem cell (CSC) functionality and heterogeneity, facilitating enrichment and personalized drug testing within 8 days.
- The platform predicted clinical outcomes in 16 breast cancer patients with approximately 93.8% accuracy, highlighting its translational potential for precision medicine.