Atopic dermatitis - PubMed
an hour ago
- #immune response
- #atopic dermatitis
- #inflammatory skin disease
- Atopic dermatitis (AD) is the most common inflammatory skin disease with high global disability burden, characterized by intense itching.
- AD is associated with comorbidities including type 2 immune-driven allergies, mental health disorders, bone health issues, infections, and other immune-mediated diseases.
- Onset can occur at any life stage, commonly in early childhood but increasingly after age 60, with recent insights into skin barrier, immune, microbiome, and neural interactions.
- Advances in understanding have led to targeted biologic therapies and small molecules for severe cases, and next-generation treatments for mild to moderate disease, though global access remains unequal.
- The authors disclose multiple financial relationships with pharmaceutical companies related to AD treatments and research.