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The impact of maternal vitamin D levels during pregnancy and risk of autism spectrum disorder and attention deficit hyperactivity disorder diagnosis and symptoms in offspring: a systematic review and

4 hours ago
  • #pregnancy
  • #vitamin D
  • #neurodevelopmental disorders
  • Higher maternal vitamin D levels during pregnancy are inversely associated with reduced risk of Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) diagnoses and symptoms in offspring.
  • The meta-analysis found a 9% decrease in ASD risk for every 10 nmol/L increase in maternal serum vitamin D levels, with a linear dose-response relationship and no evidence of thresholds.
  • There is a suggestion to assess and potentially supplement vitamin D during pregnancy to support fetal brain development and neuroprotection, especially in cases of deficiency.