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The allergy culprit histamine also boosts our memory

15 hours ago
  • #Histamine
  • #Memory
  • #Brain Function
  • Histamine in the brain improves memory accuracy by about 10% by enhancing novelty-linked arousal.
  • The drug pitolisant, used for narcolepsy, increases brain histamine levels and boosts memory-related brain connectivity.
  • Pitolisant is not recommended as a 'smart drug' due to potential sleep disruptions and long-term memory harm.
  • Histamine receptors in the brain are linked to learning and memory, explaining side effects of older antihistamines.
  • Research confirms histamine's role in memory applies to humans, supporting interest in treating brain conditions via histamine receptors.
  • Pitolisant helps restore impaired cognitive function in diseases but does not enhance cognition beyond normal levels.