Versatile Nano-Crosslinker Enhanced Injectable Hydrogel Toward Rapid Hemostasis and Efficient Trauma Repair - PubMed
5 hours ago
- #Injectable Hydrogel
- #Trauma Repair
- #Hemostasis
- A versatile nano-crosslinker, EPL-g-MnO2, is synthesized to create an injectable hydrogel (OSEG) for trauma repair.
- The OSEG hydrogel achieves rapid hemostasis (e.g., 24.9 seconds in rabbit cardiac hemorrhage) through a multi-bond crosslinked network.
- It provides antibacterial and pro-healing effects by degrading in wound environments, enhancing bone repair compared to commercial hemostats.
- The design aims to address uncontrolled hemorrhage, infection, and poor healing, potentially reducing trauma-related deaths.