Coagulopathy in obstetric bleeding: a narrative review and comparison with trauma-induced coagulopathy - PubMed
3 hours ago
- #postpartum haemorrhage
- #obstetric coagulopathy
- #trauma-induced coagulopathy
- Postpartum haemorrhage (PPH) is a leading cause of maternal mortality and morbidity worldwide.
- Coagulopathy in PPH can result from depletion/dilution of clotting factors or pathological fibrinogen destruction (acute obstetric coagulopathy).
- Resuscitation guidelines for PPH are often based on evidence from non-pregnant trauma populations, despite differences in physiology, cause, and type of coagulopathy.
- This narrative review compares the pathophysiology and management of obstetric haemorrhage coagulopathy with trauma-induced coagulopathy.