Sarcopenia and Physical Function in Obstructive Sleep Apnea: A Single-Centre Cross-Sectional Study (The SOSA Study) - PubMed
3 hours ago
- #muscle function
- #obstructive sleep apnea
- #sarcopenia
- Study examines sarcopenia prevalence in older Kuwaiti adults with obstructive sleep apnea (OSA), finding no independent link between OSA severity and sarcopenia after adjusting for age and BMI.
- Physical function, measured by chair stand test time, shows a modest correlation with OSA severity indices, suggesting it may be more sensitive to OSA-related changes than muscle mass alone.
- High prevalence of low Sonographic Thigh Adjustment Ratio (STAR) indicates need for population-specific normative data in high-obesity cohorts, as current cut-offs are derived from a lower BMI reference population.
- Sarcopenia assessed via ISarcoPRM algorithm; muscle thickness and strength did not differ across OSA severity groups, but age and BMI were significant predictors of sarcopenia.
- Conclusions highlight that age and BMI are dominant determinants of sarcopenia in this cohort, with OSA severity not being an independent risk factor for sarcopenia.