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Current application and future directions for the sarcopenic obesity Global Leadership Initiative (SOGLI) diagnostic algorithm - PubMed

3 hours ago
  • #Sarcopenic Obesity
  • #Diagnostic Algorithm
  • #Clinical Review
  • Sarcopenic obesity (SO) is defined by excess fat and reduced muscle mass/function.
  • The Sarcopenic Obesity Global Leadership Initiative (SOGLI) introduced a diagnostic algorithm in 2022 to standardize SO identification, including screening, assessment, and staging.
  • A review of 72 studies from 2022-2025 evaluated the algorithm's application, noting varied approaches in clinical settings.
  • For obesity screening, half used BMI and waist circumference; sarcopenia screening was less common.
  • Bioelectrical impedance analysis was the primary method for body composition assessment in SO diagnosis.
  • Hand-grip strength was the most used measure for evaluating muscle function.
  • SO staging was reported in 19% of studies, mostly as Stage II.
  • The algorithm confirmed links between SO and chronic diseases, functional decline, and higher mortality.
  • While the SOGLI algorithm is a significant advance, inconsistencies in screening and staging suggest areas for improvement.
  • Future refinements could include better standardization and integration of new biomarkers to boost clinical effectiveness.