Enteric viral infections promote systemic accelerated aging in Drosophila - PubMed
4 hours ago
- #Pathogenicity
- #Drosophila
- #Viral Aging
- Viral infections accelerate biological aging in Drosophila, with the degree of aging correlating with the pathogenicity of the virus.
- The effect is conserved across species, such as Caenorhabditis elegans, where non-pathogenic viruses cause minimal aging acceleration.
- Aging acceleration impacts multiple systemic pathways and persists even after viral clearance.
- Host factors, like the bacterial symbiont Wolbachia, can mitigate virus-induced aging.
- The study provides a framework for predicting long-term health consequences of viral infections based on their severity.