TIA-1 promotes FUNDC1-mediated mitophagy to protect against stress-induced cellular senescence - PubMed
4 hours ago
- #TIA-1 protein
- #cellular senescence
- #mitophagy
- TIA-1 promotes FUNDC1-mediated mitophagy to protect against cellular senescence.
- Stress-induced senescence reduces TIA-1 expression, impairing mitophagy and leading to mitochondrial dysfunction.
- TIA-1 directly interacts with FUNDC1 mRNA to enhance its expression via translational control.