Clinical characteristics and predictors of Mycoplasma pneumoniae pneumonia coinfection with Bordetella pertussis in children - PubMed
3 hours ago
- #pediatric pneumonia
- #coinfection predictors
- #clinical outcomes
- The study investigated coinfection of Mycoplasma pneumoniae (MP) pneumonia with Bordetella pertussis (BP) in children, comparing 40 coinfected patients with 40 MP-only controls.
- Coinfected children showed higher rates of fever and spasmodic cough, longer fever and cough duration, elevated WBC count and lymphocyte percentage, and more severe outcomes like severe pneumonia, oxygen therapy, bronchoalveolar lavage, methylprednisolone use, longer hospital stays, and higher costs.
- BP coinfection was associated with severe MP pneumonia (P = .017) and azithromycin treatment failure (P = .038), complicating clinical management and increasing disease burden.
- WBC count, lymphocyte percentage, fever duration, and cough duration had AUC values of 0.644, 0.641, 0.638, and 0.698, respectively, indicating potential as predictive factors for BP coinfection.