TYG-BMI demonstrates modestly higher predictive value compared to TYG and TYG/HDL for cardiovascular disease incidence in individuals over 45: a longitudinal cohort study - PubMed
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- #Insulin Resistance
- #Cardiovascular Disease
- #Predictive Value
- TYG-BMI shows modestly higher predictive value than TYG and TYG/HDL for cardiovascular disease (CVD) incidence in people over 45.
- The study involved 5,382 participants from the China Health and Retirement Longitudinal Study (CHARLS), using Cox regression and subgroup analyses.
- Participants in the highest quartile of TyG-BMI had a significantly increased CVD risk with a hazard ratio of 1.60.
- The association held across various subgroups including sex, residence, education, lifestyle factors, and medical history.
- A nonlinear relationship was found between TyG-BMI and CVD incidence, with a positive interaction noted with kidney disease.
- TyG-BMI is recommended as a valuable tool for clinicians assessing CVD risk compared to other TyG-related indices.