Combating Alzheimer's through sleep and exercise (CASE): A study protocol - PubMed
3 hours ago
- #Behavioral Interventions
- #Alzheimer's Disease
- #Cognitive Health
- Study investigates combined effects of sleep improvement and physical exercise on cognitive health in older adults, targeting Alzheimer's disease prevention.
- Three-arm randomized controlled trial over 8 weeks with 60 participants aged 55-80, including those with and without mild cognitive impairment.
- Interventions include sleep-only, exercise-only, and combined sleep-plus-exercise groups, using digital tools like neuromodulation headbands and trackers.
- Outcomes measured include cognitive performance via digital platforms and plasma biomarkers for brain and cardiometabolic health.
- Aims to explore potential synergistic effects and scalable delivery models for dementia risk reduction.