Interplay of Multipathway Dyslipidemia, Inflammation, and Cholesterol-Lowering Medication in Modifying Abdominal Aortic Aneurysm Risk - PubMed
3 hours ago
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- #cardiovascular risk
- Combined elevations of LDL-C, Lp(a), and remnant cholesterol (RC) increase AAA risk, especially without cholesterol-lowering medication (HR 2.53).
- Adding elevated hs-CRP to the triple-lipid elevation further raises AAA risk (HR 4.19) in non-medication users.
- Cholesterol-lowering medication attenuates associations for LDL-C and Lp(a) but not for RC or hs-CRP.
- In medication users, the highest AAA risk is associated with elevated LDL-C, RC, and hs-CRP (HR 2.46).
- Comprehensive assessment of lipid profiles and hs-CRP can improve identification of high-risk individuals for AAA prevention.