Piezo1-activated mesenchymal stem cells-derived extracellular matrix hydrogel promotes the repair of osteoporotic bone defects through osteogenic and angiogenic coupling - PubMed
2 hours ago
- #bone regeneration
- #osteogenesis
- #angiogenesis
- Piezo1-activated mesenchymal stem cell-derived extracellular matrix hydrogel (Y-ECM-gel) enhances repair of osteoporotic bone defects.
- Y-ECM-gel promotes osteogenic differentiation via PI3K/AKT signaling pathway.
- Y-ECM-gel stimulates angiogenesis in human umbilical vein endothelial cells.
- Y-ECM-gel improves bone formation and neovascularization in osteoporotic bone defects.
- Y-ECM-gel offers a minimally invasive therapeutic strategy for bone regeneration.