Plant-based diet quality and risk of age-related eye diseases: evidence from multi-cohorts with multi-omics insights - PubMed
3 hours ago
- #plant-based diet
- #multi-omics
- #age-related eye diseases
- Higher intake of a healthy plant-based diet is associated with reduced risks of age-related macular degeneration (AMD), cataract, glaucoma, and diabetic retinopathy.
- An unhealthy plant-based diet is linked to increased risks of AMD, cataract, and diabetic retinopathy, with weak or no association for retinal vein occlusion.
- Multi-omics analyses connect plant-based diet quality to biological pathways such as inflammation, lipid metabolism, glycaemic regulation, and hormonal signalling.
- Predictive models incorporating plant-based diet indices improve accuracy for AMD and cataract over traditional risk factors alone.
- The study uses data from the UK Biobank and a Tianjin cohort, applying methods like Cox regression, proteomics, metabolomics, and machine learning.