Evaluation and treatment of pericardial disease in immune-mediated inflammatory diseases - PubMed
5 hours ago
- #immune-mediated inflammatory diseases
- #rheumatology
- #pericardial disease
- Pericardial disease is common in patients with immune-mediated inflammatory diseases (IMIDs), especially systemic lupus erythematosus.
- It can present as asymptomatic effusion, acute/recurrent pericarditis, or lead to complications like tamponade and constrictive pericarditis.
- Pathophysiology relates to underlying immune dysregulation; diagnosis uses general criteria, biomarkers, and imaging.
- Initial management includes NSAIDs and colchicine, plus treatment of the underlying IMID; glucocorticoids are for poor responders.
- Use of immunosuppressive therapies depends on the underlying IMID and systemic organ involvement.
- Multidisciplinary care involving cardiologists, rheumatologists, and others is crucial for individualized treatment plans.