Sirolimus-Coated Versus Paclitaxel-Coated Balloons in the Treatment of Coronary Artery Lesions: A Systematic Review and Meta-Analysis - PubMed
3 hours ago
- #Meta-Analysis
- #Drug-Coated Balloons
- #Coronary Artery Disease
- Systematic review and meta-analysis compares sirolimus-coated balloons (SCBs) and paclitaxel-coated balloons (PCBs) for coronary artery lesions.
- Analysis includes 10 studies with 5246 patients (SCBs: 2964, PCBs: 2282) covering de novo lesions and in-stent restenosis.
- No significant differences found in safety outcomes: all-cause mortality, cardiac death, or myocardial infarction.
- No significant differences found in efficacy outcomes: target lesion failure, revascularization, major adverse cardiac events, or binary restenosis.
- Neither SCBs nor PCBs showed superiority; device selection should be based on lesion characteristics and clinical context.