Response to vaccination and immune status after intrauterine exposure to immunomodulating drugs for maternal IBD - PubMed
3 hours ago
- #Vaccination Response
- #IBD Pregnancy
- #Infant Immunity
- Infants exposed to maternal IBD immunomodulating drugs had vaccine responses comparable to or higher than controls, except for FHA and pneumococcal serotype 19F.
- Neutropenia occurred more frequently but was self-limiting; T-cell and total B-cell lymphopenia rates were similar to healthy controls.
- Low IgA levels were common in infants at 2, 6, and 12 months, but infection rates matched those reported in literature, supporting follow-up guideline development.