Identification of Genetic Diagnostic Markers for Systemic Lupus Erythematosus - PubMed
3 hours ago
- #bioinformatics
- #genetic markers
- #systemic lupus erythematosus
- Identification of five diagnostic genes for SLE (GBP1, IFI6, KLHDC8B, OAS3, ZCCHC2) using bioinformatics and Mendelian randomization.
- GBP1, IFI6, and OAS3 highlighted as core genes involved in SLE pathogenesis and immune cell infiltration.
- Study leveraged differential expression analysis, WGCNA, machine learning, and protein-protein interaction networks.