Geroprotective Agents, Including Glucagon-Like Peptide-1 Receptor Agonists, for Ocular Health - PubMed
4 hours ago
- #GLP-1 agonists
- #geroprotectors
- #ocular health
- Aging is linked to retinal diseases like AMD, DR, RVO, and glaucoma, involving neurodegeneration and microvascular injury.
- Geroprotectors, longevity-promoting drugs, are gaining interest for ocular health but their effects are not fully understood.
- GLP-1 receptor agonists may reduce glaucoma risk but have unconfirmed reports of severe optic neuropathy.
- Other geroprotective agents (e.g., metformin, statins) have uncertain ocular outcomes, creating clinical challenges.
- This review summarizes therapeutic and adverse ocular effects of geroprotectors to guide clinical practice and research.