Mental health monitoring in adolescents with SLE: associations with lupus low disease activity state and remission - PubMed
4 hours ago
- #Mental Health
- #Adolescent Health
- #Systemic Lupus Erythematosus
- Adolescents with SLE showed significant improvements in depressive symptoms (PHQ-A), anxiety (GAD-7), and sleep quality (PSQI) over 6-12 months.
- Disease activity (SLEDAI-2K) was low, and attainment of low disease activity (cLLDAS) and remission (cSLE) increased, though no associations were found between psychological measures and cLLDAS or remission.
- Active disease (SLEDAI-2K ≥5) was linked to greater fatigue at the second visit, but overall, mental health changes were independent of disease states.
- The study highlights the importance of integrating mental health monitoring into treat-to-target strategies for holistic SLE care in adolescents.