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Development and Validation of a Machine Learning Model for Predicting Serum Creatinine-Defined Acute Kidney Injury in Older Adults After Cardiac Surgery - PubMed

4 hours ago
  • #acute kidney injury
  • #machine learning
  • #cardiac surgery
  • Machine learning model LightGBM developed to predict acute kidney injury after cardiac surgery in older adults, achieving an AUC of 0.784.
  • The model was validated internally and externally using data from multiple centers, with key predictors including lactate, surgical duration, APTT, transfusion volume, and PT.
  • SHAP analysis was used to interpret the model's predictions, highlighting influential features and non-linear effects on risk.
  • The study involved 177 patients developing CSA-AKI, aiming to assist in early risk stratification and perioperative management optimization.